CBD Clinical Trials for Dogs with Epilepsy Promising
Dr. Stephanie McGrath, a neurologist at Colorado State University’s James L. Voss Veterinary Teaching Hospital, is performing CBD Clinical Trials for Dogs with epilepsy. Her initial findings from the groundbreaking study are more than promising. Notably, the research shows that 89 percent of dogs who received CBD in a clinical trial had a reduction in the frequency of seizures.
The study’s clinical objective: To assess the effect of oral cannabidiol (CBD) administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy. Idiopathic epilepsy is an inherited disorder, but its exact cause is unknown. While being the most common cause of seizures in the dog.
“This pilot study is important and it does seem like there is a positive effect from the use of CBD for dogs with epilepsy,” said McGrath. McGrath initially decided to pursue this line of research after receiving frequent calls from clients and other veterinarians with questions about CBD.
So, the CBD product used in the study was derived from a hemp plant. Hence, containing 0.3 percent or less of the psychoactive component of cannabis, THC. And randomly assigning dogs to a CBD (n = 12) or placebo (14) group. The CBD group received CBD-infused oil (2.5 mg/kg [1.1 mg/lb], PO) twice daily for 12 weeks in addition to existing antiepileptic treatments, and the placebo group received non-infused oil under the same conditions. As a result, comparing seizure activity, adverse effects, and plasma CBD concentrations between groups.
Positive Correlation of CBD concentration and seizure reduction
In addition to the distinct reduction of seizures in the group of dogs that received CBD oil, McGrath saw a significant association between the degree of seizure reduction and the amount of CBD concentration in the dog’s blood.
“It’s really exciting that perhaps we can start looking at CBD in the future as an alternative to existing anticonvulsive drugs,” she said.
CBD Clinical Trials for Dogs | Dr. Stephanie McGrath Future plans
In conclusion, among the questions, Dr. Stephanie McGrath is pursuing: Is CBD effective? What is the amount or dose to recommend for canine patients? How is it absorbed in the body? What effect does it have on things like metabolism? (Looking at how a drug or medication is absorbed in the body and metabolized is referred to pharmacokinetic analysis.)