What is the Human endocannabinoid system?
The endocannabinoid system is a system within the body whose receptors (CB1 and CB2) have an enormous impact on our health and well-being. According to UCLA research, the main function of the endocannabinoid system is to maintain bodily homeostasis—biological harmony in response to changes in the environment.
Go to UCLA Article for more information
The article adds: We now know the endocannabinoid system is involved in a wide variety of processes, including pain, memory, mood, appetite, stress, sleep, metabolism, immune function, and reproductive function.12,13 Endocannabinoids are arguably one of the most widespread and versatile signaling molecules known to man.
Is CBD most effective with or without THC?
So, studies show that CBD and THC work best together. Full Spectrum CBD Oil contains both as well as other essential parts of the cannabis plan that work together to create the ‘entourage effect’. Scientific studies have established that CBD and THC interact synergistically to enhance each other’s therapeutic effects. And extensive clinical research has demonstrated that CBD combined with THC is more beneficial for neuropathic pain than either compound as a single molecule.
How to read and understand a Third-Party CBD Lab Report?
Quality CBD products like those from Harbor Hemp offer a lab report from an independent company verifying the contents. Quality producers also provide individual lab reports by batch number as does Harbor Hemp. An example report is below. So, then the question is how to read and understand a Third-Party CBD Lab Report?
Well first, check if the CBD content is what is represented by the manufacturer. Huh? If you go on Amazon and buy ‘CBD’ you will be surprised that there is NO CBD in the products sold on Amazon! So if you are buying a 30ml bottle with 17mg/ml (milligrams per milliliter) of CBD, the lab report should show a CBD level > 17mg / ml – that’s what you are paying for!
In addition, you should look for the Cannabinoid profile which shows how much THC and other ‘full spectrum’ cannabinoids are present. THC should be < 0.3%.
You will also find CBC or Cannabichromene. CBC is a non-psychoactive cannabinoid that also offers potential therapeutic benefits. CBC appears to fight inflammation and reduce pain.
And Harbor Hemp full spectrum CBD products may include CBDv or Cannabidivarin. CBDv appears to minimize nausea associated with several conditions, and help to reduce inflammation.batch-201940-fso-500-mg-30-ml-w-terp
What is the CBC in CBD Oil?
CBC or Cannabichromene is a non-psychoactive cannabinoid that also offers potential therapeutic benefits. While usually contained only found in Full Spectrum CBD Oils. CBC appears to fight inflammation and reduce pain. Hence, contributing to the ‘entourage effect’ of several cannabinoids working together.
CBD Entourage Effect | What is it?
The CBD entourage effect is that individual cannabinoids, like CBD, increase their efficacy when working in conjunction with other cannabinoids, like THC or CBN. This is true even when the presence of those other cannabinoids is minimal. The whole is greater than the sum of its parts.
The entourage effect becomes evident when comparing the effects of CBD or THC in isolation with the effects of using the whole plant. Over 85 cannabinoids have been found to work in conjunction with CBD to produce the relief that is often reported by cannabis users. Full Spectrum CBD Oil provides the ‘entourage’ effect.
You can read more about the CBD entourage effect here
What is CBD oil?
CBD oil or cannabidiol oil is a substance derived from the hemp or cannabis plant.
Most CBD oil comes from industrial hemp. And not from psychoactive marijuana strains. Although the plants are related, industrial hemp does not contain nearly as much psychoactive tetrahydrocannabiol (THC). So, according to the 2014 Farm Bill, industrial hemp cannot contain more than 0.3 percent THC on a dry weight basis – an amount that is non-psychoactive.
What are the benefits of CBD?
CBD has therapeutic properties that may help people and pets that suffer from a range of conditions – including inflammation, pain, stress, headaches, trouble sleeping, skin issues, digestive problems, and many chronic diseases. To learn more about the benefits of CBD, visit ProjectCBD.org.
How does CBD work?
CBD interacts with our body’s endocannabinoid system. When you use CBD, it triggers CB1 and CB2 receptors, impacting a variety of physiological processes that can affect our brain as well as our body’s immune, digestive and nervous systems. To learn more, visit ProjectCBD.org.
What are Terpenes in CBD?
So, you’ve experienced Terpenes all your life. They give an orange its citrusy smell and pine trees their unique aroma. They are the chemicals that determine how things smell.
Terpenes are essential oils found in plants. There are around 200 terpenes in cannabis. And of course giving cannibis its distinct aroma and flavor. Terpenes have beneficial effects and work synergistically with cannabinoids like CBD and THC – this relationship is called the entourage effect.
The entourage effect essentially means that cannabinoids such as THC and CBD, along with the terpenes, are meant to work together. It’s the whole plant that does the best job, not just a single compound. It’s the difference between CBD Isolate and Full Spectrum CBD. Utilizing all the compounds and terpenes in the plant should be a consideration when choosing a CBD oil.
Is there a difference between CBD oil and hemp oil?
Yes! CBD oil includes cannabidiol. Hemp oil does not. CBD oil, sometimes called CBD tincture, is a liquid concentrate of CBD. Hemp oil is a food product made from pressed hemp seeds. Therefore, hemp oil is a food product which contains no CBD. It costs far less than CBD Oil because it contains no CBD and hence does not have CBD’s benefits.
What is driving CBD product prices?
So, there are several factors driving the price of CBD. The most significant is the limited supply vs. the overwhelming demand.
First, on the supply side, the imbalance is due to the fact that hemp farming was generally illegal prior to the passage of the Farm Bill of 2018 (Agricultural Improvement Act of 2018), signed into law on December 20, 2018. Prior to that, hemp farming was only permitted in several states and mainly for research purposes. Hence, the Farm bill authorized the farming of “industrial hemp,” that is, hemp with less than 0.3 percent THC. Of course, THC is the psychoactive element of cannabis.
As you know, CBD is derived from hemp or cannabis plans. Most importantly, we are just now in the first full growing season since the 2018 Farm Bill. In addition, this first season is limited due to the lack of defined hemp farming guidelines issued by the USDA. Finally, each state must then either implement the federal guidelines or develop their own plan for regulating hemp farming.
Bottom line, it may take several years before supply catches up with demand.
Is CBD Oil Safe for Cats?
First, there have been no scientific studies that specifically investigate the impact of cannabis on pets. But Dr. Gary Richter, a holistic veterinarian and owner and medical director of Montclair Veterinary Hospital and Holistic Veterinary Care in Oakland, California, says that CBD oil is generally safe for cats.
In addition: “I think the bigger issue, from a medical perspective, is making sure that animals are dosed appropriately. This means that the CBD oil is having the affect you want it to have, and that you’re not accidentally overdosing.”
Bottom line – check with your Veterinarian first!
You can refer to: CBD Oil for Cats | PetMD
What is CBD isolate?
CBD isolate is a crystalline powder that contains virtually pure CBD with 0% THC. It is called Isolate because it is separated from all the other plant matter contained in the hemp plant. So the oils, waxes, chlorophyll, THC and other ‘full spectrum’ materials are removed. Hence, offering a finished product usually as an oil, that’s CBD with 0% THC and nothing more.
CBD isolate can either be synthesized in a lab (synthetic CBD) or made from a CBD containing plant like cannabis or hemp.
How is CBD Made?
CBD may be derived from high quality industrial hemp (cannabis) through any of two (2) types of manufacturing processes. Plus, a set of post-extraction processes may further refine the results.
So, the current industry standard process uses carbon dioxide to extract key ingredients from the plant. It uses pressure to filter the plants key components. Hence, delivering the cannabinoids, terpenes and flavonoids found in full spectrum CBD oil.
While another process uses ethanol acting as a solvent to extract the plant’s components. It turns out Solvent Extraction is a less expensive process. However, the process may reduce the efficacy of the resultant CBD ingredients.
And there is a post-extraction set of processes designed to further purify the results from initial manufacturing process. The most relevant is one which extracts CBD Isolate from the full spectrum result in carbon dioxide extraction. This removes everything but 99%+ pure CBD with 0% THC. However, the other cannabinoids, terpenes and flavonoids removal may affect how an individual benefits from CBD.
Can you Overdose or take too much CBD?
According to a study published in the journal of Current Drug Safety, one would have to consume over 20,000mg of CBD oil in a very short amount of time. That would be 40 Bottles of 500mg CBD Oil or 1,200 common 1ml doses.
The article adds that chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans. In addition, it says CBD does not induce changes on food intake and does not affect physiological parameters (heart rate, blood pressure and body temperature). In addition, CBD does not alter psycho-motor or psychological functions.
The article abstract may be found here.